Nurturing Care for Small and Sick Newborns: Evidence Review and Country Case Studies

In 2018, WHO and partners launched the Nurturing Care Framework for Early Childhood Development.  The framework draws on state-of-the-art evidence regarding early childhood development to guide the design of policies and services to ensure that parents and caregivers are providing nurturing care for babies. Within this framework (which pertains to all newborns, infants and children from zero to three years) Every Preemie and partners identified a need for specific guidance for small and sick newborns.

Led by WHO, a group of global partners (including UNICEF, USAID, Every Preemie—SCALE and the USAID-funded Maternal and Child Survival Program [MCSP]) convened to develop an evidence synthesis report. This report summarizes the evidence and best practices on nurturing care approaches for small and sick newborns focusing on core elements of developmentally supportive care, which is disease-independent but vital to promoting healthy growth and well-being. The document is arranged in three sections:

    • Evidence Synthesis: An updated evidence review of the core elements of developmentally supportive, family-centered, and nurturing care from existing evidence synthesis documents, peer-reviewed journals, as well as grey literature;
    • Country Case Studies: Implementation experience from seven selected countries representing high-, middle- and low-income settings collected through interviews with key informants;
    • Gap analysis: A gap analysis based on evidence review and implementation experience to inform future research.

This report is closely aligned with the simultaneous development of standards of care by WHO, and provides insights for global and national stakeholders on the current status, and what is needed to enable and improve the inpatient environment for nurturing care of small and sick newborns.

Download Nurturing Care for Small and Sick Newborns


Continuum of Care for the Prevention of Preterm Birth, Management of Preterm Labor and Delivery, and Care of the Preterm and Small Newborn

This continuum of care matrix designed by Every Preemie—SCALE outlines key interventions for the prevention of preterm birth, the management of preterm labor, and care for the preterm or small newborn across two continuums—from the household/community to the health center and hospital, and from pre-pregnancy and pregnancy through labor, delivery and care of the preterm newborn.

Download Continuum of Care Matrix


Antenatal Corticosteroids for Women at Risk of Imminent Preterm Birth in the Democratic Republic of the Congo, Ethiopia, Malawi, Nigeria, Sierra Leone, Tanzania and Uganda: A Policy and Implementation Landscape Analysis

ACS is one of thirteen critical commodities identified by the United Nations Commission on Life Saving Commodities for Women and Children (UNCoLSC) and is one of ten interventions in the WHO Recommendations for interventions to improve preterm birth outcomes, 2015. In early-2016, the USAID-funded Every Preemie—SCALE project was asked by the UNCoLSC Newborn Health Technical Resource Team to conduct a policy and implementation landscape analysis of ACS use for women at risk of imminent preterm birth. The report and annexes are available for download below.

In December 2018, Every Preemie published an article in Global Health: Science and Practice (GHSP) summarizing the policy and implementation landscape analysis of antenatal corticosteroid (ACS) use for women at risk of preterm birth in seven Sub-Saharan African countries. That article is available here.

Download ACS Policy and Implementation Landscape Analysis

Download ACS Policy and Implementation Landscape Analysis Annexes


Survive and Thrive: Transforming care for every small and sick newborn

Every Preemie worked with WHO, UNICEF, USAID, the Bill and Melinda Gates Foundation, and other partners to develop a global document on inpatient care of small and sick newborns. The report outlines the efforts required to transform care for the 30 million vulnerable newborns around the world, and will be launched in mid-2019.

In advance of the full document, a summary of Key Findings from this report was launched on December 13, 2018 at the Partners’ Forum of the Partnership for Maternal, Newborn and Child Health (PMNCH) in New Delhi, India. The full document is available on Healthy Newborn Network.


International Joint Statements on Preterm Birth, Quality of Care, Kangaroo Mother Care, and Managing Serious Bacterial Infections in Young Children – February 15, 2017

On February 15, 2017, four international joint statements were released during the launch of the Quality of Care Network in Lilongwe, Malawi. The joint statements, developed in collaboration with professional health associations and supported by USAID and other partners, demonstrate how professional associations can work powerfully together in support of quality of care objectives at both global and country levels.

The international joint statement on preterm birth, developed by Every Preemie—SCALE and GAPPS, was endorsed by COINN, ICM, ICN, FIGO, IPA, AAP, ACNM, and ACOG, and affirms their support for the 2015 WHO Recommendations on interventions to improve preterm birth outcomes.  The joint statement emphasizes the important, collaborative role professional organizations have in assisting countries to implement the WHO recommendations and details clear actions needed to support their safe and effective implementation.


Do No Harm Technical Brief Series – See details here.

Global Family-Led Care Package – See details here.

Situation Analysis of Inpatient Care of Newborns and Young Infants – See details here.

Country Profiles – See details here.